Genomes

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Hundreds of genomes have been completely sequenced in the past decade, significantly advancing our understanding of genome structure and function. Genomes comprises a collection of review articles reprinted from the 10th Anniversary Issue of the journal Genome Research that captures the status of genomic research in a selection of model species-from microbes to human.

Written by renowned leaders in the field of genomics, each chapter focuses on what has been learned from the genomes of a given kingdom, group, or species and offers a unique perspective on the history, the current status, and the future of genomic research efforts. A variety of topics are addressed, including gene regulatory networks in the fruit fly and the sea squirt, fungal genome evolution, mouse and rat mutagenesis, and the future of crop plant genomics. How livestock genomics informs human medicine, the importance of the dog genome in studying human disease, and the search for "humanness" through human and chimp genome comparisons are also presented in thoughtful discussions. In addition, updates on emerging technologies in DNA sequencing and in gene prediction, as well as direction to relevant public resources, are given.

This book serves as a valuable reference and teaching tool for established scientists in the genomics field and as a comprehensive overview for those with more general interests in biology.

Table of Contents

Articles

Hillary E. Sussman, Maria A. Smit
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i-x
Claire M. Fraser-Liggett
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1-17
Kara Dolinski, David Botstein
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19-39
James E. Galagan, Matthew R. Henn, Li-Jun Ma, Christina A. Cuomo, Bruce Birren
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41-69
Michael Bevan, Sean Walsh
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71-96
Andrew H. Paterson, Michael Freeling, Takuji Sasaki
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97-116
LaDeana W. Hillier, Alan Coulson, John I. Murray, Zhirong Bao, John E. Sulston, Robert H. Waterston
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117-141
Michael Ashburner, Casey M. Bergman
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143-158
Weiyang Shi, Michael Levine, Brad Davidson
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159-175
Hugues Roest Crollius, Jean Weissenbach
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177-197
Enrique Amaya
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199-220
David W. Burt
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221-236
James E. Womack
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237-254
Elaine A. Ostrander, Robert K. Wayne
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255-279
Jozef Lazar, Carol Moreno, Howard J. Jacob, Anne E. Kwitek
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281-311
Jean Louis Guénet
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313-343
Lorraine Flaherty, Bruce Herron, Derek Symula
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345-356
Ajit Varki, Tasha K. Altheide
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357-393
Peter F.R. Little
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395-412
Michael L. Metzker
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413-438
Michael R. Brent
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439-463
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465-475