The third edition of this successful monograph has been both updated and broadened. Since the second edition was published in 2000, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Our understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerably. In addition, as the new title states, the current manifestation of this authoritative volume has a significant focus on the role of translational control in human development and disease. This book, with its 30 chapters written by experts in the field, is essential reading for anyone interested in the process of translation, its regulation, and how its failure can cause disease.

REVIEWS OF THE SECOND EDITION

"I strongly recommend this publication as an authoritative source-book, both for students entering the field and established practitioners alike, and it should find its way onto many laboratory benches and library shelves."

-Trends in Genetics

"Whether you are an advanced student or an experienced researcher, if you need to bring yourself up to speed on the translational control of gene expression, then this is the book for you... . As you would expect from a Cold Spring Harbor Monograph, the volume is comprehensive, scholarly and as 'up-to-date' as this type of multi-author volume can hope to be. I can recommend this volume to individual specialists and institutional libraries, both of which will get a lot of good value for their money."

-Microbiology Today