This volume is a new edition of the most authoritative book on Prion Biology, first published in 1999 and edited by the Nobel Prize-winning founder of the field. This expanded edition has been completely updated, and includes chapters on therapeutics, and diagnostic methods and approaches.

CRITICAL PRAISE FOR THE FIRST EDITION

"Prion Biology and Diseases is by far the most authoritative introduction and summary of the complex data that form the basis of our understanding of the molecular basis of this esoteric group of diseases. While the human forms of the diseases are rare, their economic impact, particularly in the United Kingdom, has been profound. Moreover, their occurrence is now threatening the normal operation of blood-transfusion services worldwide. Hence the need for such an authoritative book. It is the best comprehensive overview of this field and is an ideal introduction for anyone wishing to launch a career in prionology."

-Nature

"All in all, this book is a good read. All the necessaries are there but the style is light and accessible. I would recommend this book to anybody, whether they work in the field and want a concise summary of the state of prion research, or are only now entering the fascinating world of the prion."

-Trends in Neurosciences

"This book is a testament to the tremendous contributions of Prusiner and his collaborators in the field of prion research."

-New England Journal of Medicine

"Prusiner has brought together an impressive amount of scientific data dealing with prions (a word he coined). This book is a must for anyone interested in the prion field. For those not familiar with the field, the book provides ample introduction. The book is an invaluable reference source combining clinical, epidemiological, genetic, and biochemical data. An exhaustive amount of material is presented dealing with everything from how to isolate prions to strategies for analyzing PrP structure."

-Cell