Cell Growth: Control of Cell Size (2004, Volume 42)

Cover Page

How is the growth of a cell regulated? And how is that growth coordinated as the cell progresses through the division cycle? These are important questions in biology. If the signaling pathways that control growth go awry, the cells produced are too large or too small, leading to developmental abnormalities and errors and contributing to a variety of pathological conditions that include cancer, diabetes, and inflammation.

Fundamentally important and clinically relevant, the topic receives the close attention it deserves in Cell Growth: Control of Cell Size. With contributions from internationally renowned experts, the book discusses cell growth in the context of both development and cell division. It focuses on individual molecules and mechanisms that control cell size and describes cell growth in specific tissues. This volume serves as a valuable reference for established scientists in the field, as well as a superb introduction for those with more general interests in animal and plant cell biology.

Table of Contents

Preface/Front Matter
Michael N. Hall, Martin Raff, George Thomas
Excerpt       PDF     (i-xii)
 
1 How Metazoans Reach Their Full Size: The Natural History of Bigness
Patrick H. O’Farrell
Excerpt       PDF     (1-22)
 
2 Growth and Cell Cycle Control in Drosophila
Bruce A. Edgar, H. Frederik Nijhout
Excerpt       PDF     (23-83)
 
3 Coordination of Cell Growth and Cell-cycle Progression in Proliferating Mammalian Cells
Ian Conlon, Alison Lloyd, Martin Raff
Excerpt       PDF     (85-99)
 
4 Coordination of Cell Growth and Cell Division
Emmett Vance Schmidt
Excerpt       PDF     (101-137)
 
5 TOR Signaling in Yeast: Temporal and Spatial Control of Cell Growth
Robbie Loewith, Michael N. Hall
Excerpt       PDF     (139-165)
 
6 Growth Regulation by Insulin and TOR Signaling in Drosophila
Sally J. Leevers, Ernst Hafen
Excerpt       PDF     (167-192)
 
7 Growth Control through the mTOR Network
David A. Guertin, Do-Hyung Kim, David M. Sabatini
Excerpt       PDF     (193-234)
 
8 IGF-I Receptor Signaling in Cell Growth and Proliferation
Renato Baserga
Excerpt       PDF     (235-263)
 
9 S6K Integrates Nutrient and Mitogen Signals to Control Cell Growth
Jacques Montagne, George Thomas
Excerpt       PDF     (265-298)
 
10 Translation Initiation and Cell Growth Control
Emmanuel Petroulakis, Nahum Sonenberg
Excerpt       PDF     (299-328)
 
11 Forging the Factory: Ribosome Synthesis and Growth Control in Budding Yeast
Paul Jorgensen, Mike Tyers, Jonathan R. Warner
Excerpt       PDF     (329-370)
 
12 Control of rRNA and tRNA Production Is Closely Tied to Cell Growth
Robert J. White
Excerpt       PDF     (371-412)
 
13 Autophagy: Reversing Cell Growth
Yoshinori Ohsumi
Excerpt       PDF     (413-429)
 
14 Synaptic Growth, Synaptic Maintenance, and the Persistence of Long-term Memory Storage
Craig H. Bailey, Robert D. Hawkins, Eric R. Kandel
Excerpt       PDF     (431-472)
 
15 Control of Synaptic Function by Local Protein Synthesis and Degradation
W. Bryan Smith, Baris Bingol, Gentry N. Patrick, Erin M. Schuman
Excerpt       PDF     (473-507)
 
16 Lymphocyte Growth
Daniel E. Bauer, Craig B. Thompson
Excerpt       PDF     (509-527)
 
17 Modulating Skeletal Muscle Hypertrophy and Atrophy: Signaling Pathways and Therapeutic Targets
David J. Glass, George D. Yancopoulos
Excerpt       PDF     (529-548)
 
18 Mechanisms Controlling Heart Growth in Mammals
Julie R. McMullen, Seigo Izumo
Excerpt       PDF     (549-603)
 
19 Regulation of Cell Growth in the Endocrine Pancreas
Kristin Roovers, Morris J. Birnbaum
Excerpt       PDF     (605-623)
 
20 Plant Cell Growth
Benoît Menand, Christophe Robaglia
Excerpt       PDF     (625-637)
 
Subject Index
Excerpt       PDF     (639-652)