Translational Control of Gene Expression (2000, Volume 39)

Cover Page

The editors are to be congratulated on assembling a high-powered collection of expert contributors to produce this large monograph, and, if you are seeking a snapshot of all the major topics of importance in the field of protein synthesis (particularly in eukaryotes) at the beginning of the 21st century, Translational Control of Gene Expression is the place to look... . I strongly recommend this publication as an authoritative source book, both for students entering the field and established practitioners alike, and it should find its way onto many laboratory benches and library shelves.

-Trends in Genetics

This book is the most complete and up-to-date review of translational control mechanisms. It is a must for students entering the field, and it will constitute for many years a major reference guide for an investigator who is seriously interested in the full picture of gene expression.

-Journal of Cell Science

Whether you are an advanced student or an experienced researcher, if you need to bring yourself up to speed on the translational control of gene expression, then this is the book for you. In 36 chapters almost every aspect of translational control, including the mechanisms of initiation, elongation and termination, control during development, control in response to extracellular stimuli and control during virus infection or cancer are dealt with. As you would expect from a Cold Spring Harbor Monograph, the volume is comprehensive, scholarly and as 'up-to-date' as this type of multi-author volume can hope to be... . I can recommend this volume to individual specialists and institutional libraries, both of which will get a lot of good value for their money.

-Microbiology Today

Table of Contents

Preface/Front Matter
N. Sonenberg, J.W.B. Hershey, M.B. Mathews
Excerpt       PDF     (i-x)
 
1 Origins and Principles of Translational Control
Michael B. Mathews, Nahum Sonenberg, John W.B. Hershey
Excerpt       PDF     (1-31)
 
2 The Pathway and Mechanism of Initiation of Protein Synthesis
John W. B. Hershey, William C. Merrick
Excerpt       PDF     (33-88)
 
3 The Protein Biosynthesis, Elongation Cycle
William C. Merrick, Jens Nyborg
Excerpt       PDF     (89-125)
 
4 A Comparative View of Initiation Site Selection Mechanisms
Richard J. Jackson
Excerpt       PDF     (127-183)
 
5 Mechanism and Regulation of Initiator Methionyl-tRNA Binding to Ribosomes
Alan G. Hinnebusch
Excerpt       PDF     (185-243)
 
6 Regulation of Ribosomal Recruitment in Eukaryotes
Brian Raught, Anne-Claude Gingras, Nahum Sonenberg
Excerpt       PDF     (245-293)
 
7 Translational Control of Developmental Decisions
Marvin Wickens, Elizabeth B. Goodwin, Judith Kimble, Sidney Strickland, Matthias W. Hentze
Excerpt       PDF     (295-370)
 
8 Viral Translational Strategies and Host Defense Mechanisms
Tsafi Pe’ery, Michael B. Mathews
Excerpt       PDF     (371-424)
 
9 Ribosomal Subunit Joining
Tatyana V. Pestova, Christopher U.T. Hellen, Thomas E. Dever
Excerpt       PDF     (425-445)
 
10 Physical and Functional Interactions between the mRNA Cap Structure and the Poly(A) Tail
Alan Sachs
Excerpt       PDF     (447-465)
 
11 Translation Termination: It’s Not the End of the Story
Ellen M. Welch, Weirong Wang, Stuart W. Peltz
Excerpt       PDF     (467-485)
 
12 Genetic Approaches to Translation Initiation in Saccharomyces cerevisiae
Thomas F. Donahue
Excerpt       PDF     (487-502)
 
13 The Double-stranded RNA-activated Protein Kinase PKR
Randal J. Kaufman
Excerpt       PDF     (503-527)
 
14 Heme-regulated eIF2α Kinase
Jane-Jane Chen
Excerpt       PDF     (529-546)
 
15 PERK and Translational Control by Stress in the Endoplasmic Reticulum
David Ron, Heather P. Harding
Excerpt       PDF     (547-560)
 
16 Regulation of Translation Initiation in Mammalian Cells by Amino Acids
Scot R. Kimball, Leonard S. Jefferson
Excerpt       PDF     (561-579)
 
17 Translational Control during Heat Shock
Robert J. Schneider
Excerpt       PDF     (581-593)
 
18 Translational Control by Upstream Open Reading Frames
Adam P. Geballe, Matthew S. Sachs
Excerpt       PDF     (595-614)
 
19 Cellular Internal Ribosome Entry Site Elements and the Use of cDNA Microarrays in Their Investigation
Mark S. Carter, Kenneth M. Kuhn, Peter Sarnow
Excerpt       PDF     (615-635)
 
20 Translational Control and Cancer
John W. B. Hershey, Suzanne Miyamoto
Excerpt       PDF     (637-654)
 
21 Translational Control of Ferritin Synthesis
Tracey A. Rouault, Joe B. Harford
Excerpt       PDF     (655-670)
 
22 Translational Control of TOP mRNAs
Oded Meyuhas, Eran Hornstein
Excerpt       PDF     (671-693)
 
23 S6 Phosphorylation and Signal Transduction
Stefano Fumagalli, George Thomas
Excerpt       PDF     (695-717)
 
24 Control of the Elongation Phase of Protein Synthesis
Christopher Proud
Excerpt       PDF     (719-739)
 
25 Programmed Translational Frameshifting, Hopping, and Readthrough of Termination Codons
Philip J. Farabaugh, Qiang Qian, Guillaume Stahl
Excerpt       PDF     (741-761)
 
26 Recoding UGA as Selenocysteine
Marla J. Berry
Excerpt       PDF     (763-783)
 
27 Influence of Polyadenylation-induced Translation on Metazoan Development and Neuronal Synaptic Function
Joel D. Richter
Excerpt       PDF     (785-805)
 
28 Interaction of mRNA Translation and mRNA Degradation in Saccharomyces cerevisiae
David C. Schwartz, Roy Parker
Excerpt       PDF     (807-825)
 
29 Destabilization of Nonsense-containing Transcripts in Saccharomyces cerevisiae
Allan Jacobson, Stuart W. Peltz
Excerpt       PDF     (827-847)
 
30 Nonsense-mediated RNA Decay in Mammalian Cells: A Splicing-dependent Means to Down-regulate the Levels of mRNAs That Prematurely Terminate Translation
Lynne E. Maquat
Excerpt       PDF     (849-868)
 
31 Translation Initiation on Picornavirus RNA
Graham J. Belsham, Richard J. Jackson
Excerpt       PDF     (869-900)
 
32 Adenovirus Inhibition of Cellular Protein Synthesis and Preferential Translation of Viral mRNAs
Robert J. Schneider
Excerpt       PDF     (901-914)
 
33 Reovirus Translational Control
Aaron J. Shatkin
Excerpt       PDF     (915-932)
 
34 Translational Reprogramming during Influenza Virus Infection
Seng-Lai Tan, Michael G. Katze, Michael J. Gale, Jr.
Excerpt       PDF     (933-950)
 
35 Translational Control in Poxvirus-infected Cells
Bertram L. Jacobs
Excerpt       PDF     (951-971)
 
36 Nontranslational Functions of Components of the Translational Apparatus
Terri Goss Kinzy, Emanuel Goldman
Excerpt       PDF     (973-997)
 
Index
Excerpt       PDF     (999-1020)