
CRITICAL ACCLAIM FOR THE RNA WORLD
The first edition of The RNA World, edited by Ray Gesteland and John Atkins ... appeared six years ago. The enormous progress made since then has prompted the editors, now joined by Tom Cech, to produce an impressive second edition. About half of the 24 chapters update contributions to the first edition; the remainder are entirely new chapters, also written by eminent experts.
-Science
The book contains a wealth of information in a condensed form and thus, for some years to come, will constitute a gold mine of bibliographic value even for those specializing in the various areas that are covered ... . All in all, a great book!
-Cell
Each chapter has the perspective and depth that comes from a knowledgeable authority-the book has a stellar list of authors ... . Overall, the book is splendid and a 'must' for serious practitioners in the field. It is also essential for students taking graduate courses in nucleic acids.
-Trends in Biochemical Sciences
The book ... serves as an excellent reference for the structure, function, and enzymology of RNA ... highly useful for those working in the RNA field, and also as a textbook in graduate courses.
-The Quarterly Review of Biology
There is more to marvel at in the structure and function of RNA in this world than in the dimly perceived world that RNA may have called its own. One cannot help but think of this as a wonderful achievement, and perhaps the best reason for recommending The RNA World.
-RNA
Table of Contents
| Preface/Front Matter |
| R. F. Gesteland, T. R. Cech, J. F. Atkins |
| Excerpt PDF (i-xxv) |
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| 1 Before RNA and After: Geophysical and Geochemical Constraints on Molecular Evolution |
| Stephen J. Mojzsis, Ramanarayanan Krishnamurthy, Gustaf Arrhenius |
| Excerpt PDF (1-47) |
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| 2 Prospects for Understanding the Origin of the RNA World |
| Gerald F. Joyce, Leslie E. Orgel |
| Excerpt PDF (49-77) |
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| 3 The Genomic Tag Hypothesis: What Molecular Fossils Tell Us about the Evolution of tRNA |
| Nancy Maizels, Alan M. Weiner |
| Excerpt PDF (79-111) |
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| 4 Probing RNA Structure, Function, and History by Comparative Analysis |
| Norman R. Pace, Brian C. Thomas, Carl R. Woese |
| Excerpt PDF (113-141) |
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| 5 Re-creating an RNA Replicase |
| David P. Bartel |
| Excerpt PDF (143-162) |
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| 6 Did the RNA World Exploit an Expanded Genetic Alphabet? |
| Steven A. Benner, Petra Burgstaller, Thomas R. Battersby, Simona Jurczyk |
| Excerpt PDF (163-181) |
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| 7 Aminoacyl-tRNA Synthetases and Self-acylating Ribozymes |
| Michael Yarus, Mali Illangasekare |
| Excerpt PDF (183-196) |
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| 8 On the Origin of the Ribosome: Coevolution of Subdomains of tRNA and rRNA |
| Harry F. Noller |
| Excerpt PDF (197-219) |
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| 9 Introns and the RNA World |
| Walter Gilbert, Sandro J. De Souza |
| Excerpt PDF (221-231) |
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| 10 The Interactions That Shape RNA Structure |
| Mark E. Burkard, Douglas H. Turner, Ignacio Tinoco, Jr. |
| Excerpt PDF (233-264) |
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| 11 Small Ribozymes |
| David B. McKay, Joseph E. Wedekind |
| Excerpt PDF (265-286) |
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| 12 The Role of Metal Ions in RNA Biochemistry |
| Andrew L. Feig, Olke C. Uhlenbeck |
| Excerpt PDF (287-319) |
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| 13 Building a Catalytic Active Site Using Only RNA |
| Thomas R. Cech, Barbara L. Golden |
| Excerpt PDF (321-349) |
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| 14 Ribonuclease P |
| Sidney Altman, Leif Kirsebom |
| Excerpt PDF (351-380) |
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| 15 The RNA Folding Problem |
| Peter B. Moore |
| Excerpt PDF (381-401) |
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| 16 RNA Interaction with Small Ligands and Peptides |
| Joseph D. Puglisi, James R. Williamson |
| Excerpt PDF (403-425) |
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| 17 RNA Recognition by Proteins |
| Thomas A. Steitz |
| Excerpt PDF (427-450) |
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| 18 Group I and Group II Ribozymes as RNPs: Clues to the Past and Guides to the Future |
| Alan M. Lambowitz, Mark G. Caprara, Steven Zimmerly, Philip S. Perlman |
| Excerpt PDF (451-485) |
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| 19 The Growing World of Small Nuclear Ribonucleoproteins |
| Yi-Tao Yu, Elizabeth C. Scharl, Christine M. Smith, Joan A. Steitz |
| Excerpt PDF (487-524) |
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| 20 Splicing of Precursors to mRNAs by the Spliceosomes |
| Christopher B. Burge, Thomas Tuschl, Phillip A. Sharp |
| Excerpt PDF (525-560) |
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| 21 tRNA Splicing: An RNA World Add-on or an Ancient Reaction? |
| Christopher R. Trotta, John Abelson |
| Excerpt PDF (561-584) |
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| 22 RNA Editing—An Evolutionary Perspective |
| Larry Simpson |
| Excerpt PDF (585-608) |
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| 23 Telomerase |
| Elizabeth H. Blackburn |
| Excerpt PDF (609-635) |
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| 24 Dynamics of the Genetic Code |
| John F. Atkins, August Böck, Senya Matsufuji, Raymond F. Gesteland |
| Excerpt PDF (637-673) |
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| APPENDIX 1: Structures of Base Pairs Involving at Least Two Hydrogen Bonds |
| Mark E. Burkard, Douglas H. Turner, Ignacio Tinoco, Jr. |
| Excerpt PDF (675-680) |
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| APPENDIX 2: Schematic Diagrams of Secondary and Tertiary Structure Elements |
| Mark E. Burkard, Douglas H. Turner, Ignacio Tinoco, Jr. |
| Excerpt PDF (681-685) |
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| APPENDIX 3: Reactions Catalyzed by RNA and DNA Enzymes |
| Gerald F. Joyce |
| Excerpt PDF (687-690) |
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| APPENDIX 4: Visualization of Elongation Factor Tu on the 70S E. coli Ribosome |
| Holger Stark, Marin van Heel, Marina Rodnina, Wolfgang Wintermeyer, Richard Brimacombe |
| Excerpt PDF (691-694) |
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| APPENDIX 5: The Large Ribosomal Subunit from H. marismortui at 9 Å Resolution |
| Nenad Ban, Peter B. Moore, Thomas A. Steitz |
| Excerpt PDF (695-696) |
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| Index |
| Excerpt PDF (697-709) |
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