DNA replication is a central cog in the machinery of cell and viral proliferation. After significant advances in the past few years, its regulation is now understood in unprecedented depth.

This is the first book to provide a detailed and thoroughly up-to-date review of the complexity of DNA replication in eukaryotic cells. It is organized into three parts: Concepts, a distillation of underlying principles; Enzymes, a description of each protein class involved; and Systems, a review of events over a wide range of organisms. The book is therefore invaluable for teachers who want a current survey of a topic central to the biology syllabus; investigators of replication who will appreciate a remarkably concise, central source of knowledge in their specialty; and scientists studying other biological functions on which DNA replication has an impact.