Adult Neurogenesis (2008, Volume 52)

Cover Page

The generation of new neurons in the adult mammalian brain is one of the most extraordinary examples of neuroplasticity. Bringing together leading researchers in the field of adult neurogenesis, this book provides a valuable overview of this emerging field and lays the groundwork for future studies. It includes discussions on neural stem cell biology, methods and models for studying adult neurogenesis, physiological and molecular processes and their control, related neurological diseases, and comparisons of neurogenesis in humans, birds, fish, and invertebrates. This volume will be of interest to researchers in neurobiology, as well as those with clinical interests, as it has implications for understanding depression, epilepsy, and other neurological and psychiatric disorders.

Table of Contents

Preface/Front Matter
Fred H. Gage, Gerd Kempermann, Hongjun Song
Excerpt       PDF     (i-xii)
1 Adult Neurogenesis: A Prologue
Fred H. Gage, Hongjun Song, Gerd Kempermann
Excerpt       PDF     (1-5)
2 Numerology of Neurogenesis: Characterizing the Cell Cycle of Neurostem Cells
Richard S. Nowakowski, Nancy L. Hayes
Excerpt       PDF     (7-23)
3 Detection and Phenotypic Characterization of Adult Neurogenesis
H. Georg Kuhn, Daniel A. Peterson
Excerpt       PDF     (25-47)
4 Evolving Methods for the Labeling and Mutation of Postnatal Neuronal Precursor Cells: A Critical Review
Joshua J. Breunig, Pasko Rakic, Jeffrey D. Macklis
Excerpt       PDF     (49-80)
5 The Use of Reporter Mouse Lines to Study Adult Neurogenesis
Grigori Enikolopov, Linda Overstreet-Wadiche
Excerpt       PDF     (81-100)
6 Retrovirus-mediated Cell Labeling
Chunmei Zhao
Excerpt       PDF     (101-117)
7 Neurospheres
Ilyas Singec, Alfredo Quiñones-Hinojosa
Excerpt       PDF     (119-134)
8 Monolayer Cultures of Neural Stem/Progenitor Cells
Jasodhara Ray
Excerpt       PDF     (135-157)
9 Neurogenesis in the Adult Hippocampus
Gerd Kempermann, Hongjun Song, Fred H. Gage
Excerpt       PDF     (159-174)
10 Adult Subventricular Zone and Olfactory Bulb Neurogenesis
Daniel A. Lim, Yin-Cheng Huang, Arturo Alvarez-Buylla
Excerpt       PDF     (175-206)
11 Neurogenic Niches in the Adult Mammalian Brain
Dengke K. Ma, Guo-Li Ming, Fred H. Gage, Hongjun Song
Excerpt       PDF     (207-225)
12 Adult Neurogenesis: Similarities and Differences in Stem Cell Fate, Proliferation, Migration, and Differentiation in Distinct Forebrain Regions
D. Chichung Lie, Magdalena Götz
Excerpt       PDF     (227-265)
13 Proneuronal Genes Drive Neurogenesis on the Road from Development to Adulthood
Elizabeth T. Buchen, Samuel J. Pleasure
Excerpt       PDF     (267-282)
14 The Balance of Trophic Support and Cell Death in Adult Neurogenesis
H. Georg Kuhn
Excerpt       PDF     (283-298)
15 Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus
Josef Bischofberger, Alejandro F. Schinder
Excerpt       PDF     (299-319)
16 Genetics and Epigenetics in Adult Neurogenesis
Jenny Hsieh, Jay W. Schneider
Excerpt       PDF     (321-339)
17 Activity Dependency and Aging in the Regulation of Adult Neurogenesis
Gerd Kempermann
Excerpt       PDF     (341-362)
18 Regulation of Hippocampal Neurogenesis by Systemic Factors Including Stress, Glucocorticoids, Sleep, and Inflammation
Paul J. Lucassen, Charlotte A. Oomen, Anne-Marie van Dam, Boldizsár Czéh
Excerpt       PDF     (363-395)
19 Regulation of Adult Neurogenesis by Neurotransmitters
Mi-Hyeon Jang, Hongjun Song, Guo-Li Ming
Excerpt       PDF     (397-423)
20 Adult Neurogenesis in the Olfactory Bulb
Pierre-Marie Lledo
Excerpt       PDF     (425-443)
21 Neurogenesis and Hippocampal Memory System
D. Nora Abrous, J. Martin Wojtowicz
Excerpt       PDF     (445-461)
22 Computational Modeling of Adult Neurogenesis
James B. Aimone, Laurenz Wiskott
Excerpt       PDF     (463-481)
23 Hippocampal Neurogenesis: Depression and Antidepressant Responses
Amar Sahay, Rene Hen, Ronald S. Duman
Excerpt       PDF     (483-501)
24 Adult Neurogenesis in Neurodegenerative Diseases
Patrik Brundin, Jürgen Winkler, Eliezer Masliah
Excerpt       PDF     (503-533)
25 Epilepsy and Adult Neurogenesis
Sebastian Jessberger, Jack M. Parent
Excerpt       PDF     (535-547)
26 Neurogenesis following Stroke Affecting the Adult Brain
Olle Lindvall, Zaal Kokaia
Excerpt       PDF     (549-570)
27 Adult Neurogenesis in Teleost Fish
Günther K.H. Zupanc
Excerpt       PDF     (571-592)
28 Neurogenesis in the Adult Songbird: A Model for Inducible Striatal Neuronal Addition
Steve A. Goldman
Excerpt       PDF     (593-617)
29 Adult Human Neurogenesis: A Response to Cell Loss and New Circuitry Requirements?
Maurice A. Curtis, Peter S. Eriksson, Richard L.M. Faull
Excerpt       PDF     (619-693)
30 Adult Hippocampal Neurogenesis in Natural Populations of Mammals
Irmgard Amrein, Hans-Peter Lipp, Rudy Boonstra, J. Martin Wojtowicz
Excerpt       PDF     (645-659)
Excerpt       PDF     (661-673)