The transcription of DNA into RNA lies at the heart of gene activation. It is a process tightly controlled by complex interactions between intracellular proteins and the DNA. This book is a landmark account of these controls, derived from the work of over 40 leading laboratories worldwide. It is intended as a definitive reference work for this evolving field.
Table of Contents
| 23 lac Repressor |
| Jay D. Gralla |
| Excerpt PDF (629-642) |
| 24 Regulation of the L-Arabinose Catabolic Operon araBAD |
| Robert Schleif |
| Excerpt PDF (643-665) |
| 25 Prokaryotic Transcriptional Enhancers |
| David S. Weiss, Karl E. Klose, Timothy R. Hoover, Anne K. North, Susan C. Porter, Andrew B. Wedel, Sydney Kustu |
| Excerpt PDF (667-694) |
| 26 Transcriptional Activation by Viral Immediate-Early Proteins: Variations on a Common Theme |
| Katherine J. Martin, Michael R. Green |
| Excerpt PDF (695-725) |
| 27 Adenovirus E1A trans-Activation: Understanding It Will Require Learning How the General Transcription Factors Function |
| Arnold J. Berk |
| Excerpt PDF (727-742) |
| 28 Mechanisms of Transcriptional Control as Revealed by Studies of Human Transcription Factor Sp1 |
| Albert J. Courey, Robert Tjian |
| Excerpt PDF (743-769) |
| 29 CCAAT/Enhancer Binding Protein |
| Steven L. McKnight |
| Excerpt PDF (771-795) |
| 30 Dangerous Liaisons: Fos and Jun, Oncogenic Transcription Factors |
| Tom Curran, Peter K. Vogt |
| Excerpt PDF (797-831) |
| 31 Yeast GCN4 Transcriptional Activator Protein |
| Kevin Struhl |
| Excerpt PDF (833-859) |
| 32 The Helix-Loop-Helix Motif: Structure and Function |
| Cornelis Murre, David Baltimore |
| Excerpt PDF (861-879) |
| 33 Structure and Function of Serum Response Factor |
| Richard Treisman |
| Excerpt PDF (881-905) |
| 34 Heat Shock Factor |
| John Lis, Carl Wu |
| Excerpt PDF (907-930) |
| 35 GAL11, GAL11P, and the Action of GAL4 |
| Alexander A.F. Gann, Howard J. Himmelfarb, Mark Ptashne |
| Excerpt PDF (931-946) |
| 36 Integration of Multiple Regulatory Inputs in the Control of HO Expression in Yeast |
| Ira Herskowitz, Brenda Andrews, Warren Kruger, Joseph Ogas, Anita Sil, Cara Coburn, Craig Peterson |
| Excerpt PDF (949-974) |
| 37 A Combinatorial Regulatory Circuit in Budding Yeast |
| Alexander Johnson |
| Excerpt PDF (975-1006) |
| 38 Mechanism and Regulation of Transcriptional Activation in Eukaryotes: Conserved Features from Yeasts to Humans |
| Leonard Guarente |
| Excerpt PDF (1007-1036) |
| 39 The Myogenic Helix-Loop-Helix Family: Regulators of Skeletal Muscle Determination and Differentiation |
| Andrew B. Lassar, Harold Weintraub |
| Excerpt PDF (1037-1061) |
| 40 Transcriptional Regulatory Mechanisms in Liver and Midgut Morphogenesis of Vertebrates and Invertebrates |
| Gerald R. Crabtree, Ueli Schibler, Matthew P. Scott |
| Excerpt PDF (1063-1102) |
| 41 Oct-1 and Oct-2: Differential Transcriptional Regulation by Proteins That Bind to the Same DNA Sequence |
| Winship Herr |
| Excerpt PDF (1103-1135) |
| 42 Retinoid Receptors as Transcription Factors |
| David J. Mangelsdorf, Ronald M. Evans |
| Excerpt PDF (1137-1167) |
| 43 Combinatorial Regulation at a Mammalian Composite Response Element |
| Keith R. Yamamoto, David Pearce, Jay Thomas, Jeffrey N. Miner |
| Excerpt PDF (1169-1192) |
| 44 Positive and Negative Control of Human Interferon-β Gene Expression |
| Tom Maniatis, Lisa-Anne Whittemore, Wei Du, Chen-Ming Fan, Andrew D. Keller, Vito J. Palombella, Dimitrios N. Thanos |
| Excerpt PDF (1193-1220) |
| 45 The Bicoid Morphogen: Concentration-dependent Transcriptional Activation of Zygotic Target Genes during Early Drosophila Development |
| Wolfgang Driever |
| Excerpt PDF (1221-1250) |
| 46 Template Topology and Transcription |
| James C. Wang |
| Excerpt PDF (1253-1269) |
| 47 Analysis of SPT Genes: A Genetic Approach toward Analysis of TFIID, Histones, and Other Transcription Factors of Yeast |
| Fred Winston |
| Excerpt PDF (1271-1293) |
| 48 Histones: Regulators of Transcription in Yeast |
| Michael Grunstein, Linda K. Durrin, Randall K. Mann, Grace Fisher-Adams, Lianna M. Johnson |
| Excerpt PDF (1295-1315) |
| Cumulative Author Index |
| Excerpt PDF (1317-1318) |
| Cumulative Subject Index |
| Excerpt PDF (1319-1334) |