The transcription of DNA into RNA lies at the heart of gene activation. It is a process tightly controlled by complex interactions between intracellular proteins and the DNA. This book is a landmark account of these controls, derived from the work of over 40 leading laboratories worldwide. It is intended as a definitive reference work for this evolving field.
| Preface/Front Matter |
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Keith R. Yamamoto, Steven L. McKnight |
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(i-xii) |
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| 1 Transcriptional Regulation: Elegance in Design and Discovery |
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Charles Yanofsky |
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(3-24) |
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| 2 Yeast RNA Polymerase Subunits and Genes |
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André Sentenac, Michel Riva, Pierre Thuriaux, Jean-Marie Buhler, Isabelle Treich, Christophe Carles, Michel Werner, Anny Ruet, Janine Huet, Carl Mann, Nuchanard Chiannilkulchai, Sophie Stettler, Sylvie Mariotte |
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(27-54) |
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| 3 RNA Polymerase II Subunits, Transcription Factors, and Kinases: Investigations in Drosophila melanogaster and Saccharomyces cerevisiae |
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Arno L. Greenleaf |
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(55-80) |
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| 4 Carboxy-terminal Domain of the Largest Subunit of Eukaryotic RNA Polymerase II |
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Jeffry L. Corden, C. James Ingles |
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(81-107) |
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| 5 Phosphorylation of RNA Polymerase II as a Transcriptional Regulatory Mechanism |
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Michael E. Dahmus, William S. Dynan |
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(109-128) |
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| 6 Bacterial Sigma Factors |
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Carol A. Gross, Michael Lonetto, Richard Losick |
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(129-176) |
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| 7 Quantitative Aspects of the Transcription Cycle in Escherichia coli |
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Peter H. Von Hippel, Thomas D. Yager, Stanley C. Gill |
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(179-201) |
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| 8 Protein-Protein Interactions as Critical Determinants of Regulated Initiation and Termination of Transcription |
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Jack Greenblatt |
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(203-226) |
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| 9 Initiation of Transcription by RNA Polymerase II |
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Stephen Buratowski, Phillip A. Sharp |
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(227-246) |
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| 10 RNA Polymerase III Transcription Complexes |
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E. Peter Geiduschek, George A. Kassavetis |
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(247-280) |
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| 11 Transcription of Vertebrate snRNA Genes and Related Genes |
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Nouria Hernandez |
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(281-313) |
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| 12 Regulation of Transcription by RNA Polymerase I |
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Ronald H. Reeder |
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(315-347) |
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| 13 Yeast RNA Polymerase II Transcription In Vitro: General Initiation Factors; Novel Mediator of Transcriptional Activation; Three-dimensional Structure of RNA Polymerase II |
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Roger D. Kornberg, Daniel I. Chasman, Seth A. Darst, Aled M. Edwards, William J. Feaver, Peter M. Flanagan, Opher Gileadi, N. Lynn Henry, Raymond J. Kelleher, Iii, Yang Li, Yahli Lorch, Neal F. Lue, Michael H. Sayre, Herbert Tschochner |
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(349-362) |
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| 14 Escherichia coli Rho Factor: Protein and Enzyme of Transcription Termination |
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Terry Platt, John P. Richardson |
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(365-388) |
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| 15 Antitermination and the Control of Transcription Elongation |
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Jeffrey Roberts |
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(389-406) |
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| 16 Transcriptional Attenuation |
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Robert Landick, Charles L. Turnbough, Jr. |
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(407-446) |
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| 17 Molecular Characteristics of the Regulatory Switch in Phages 434 and λ |
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Stephen C. Harrison |
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(449-473) |
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| 18 The Molecular Mechanism of trp Repression |
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Paul B. Sigler |
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(475-499) |
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| 19 Transcriptional Activation by Escherichia coli CAP Protein |
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Donald M. Crothers, Thomas A. Steitz |
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(501-534) |
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| 20 Transcriptional Regulation by Homeodomain Proteins: Structural, Functional, and Genetic Aspects |
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Kurt Wüthrich, Walter Gehring |
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(535-577) |
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| 21 Solution Structures of DNA-binding Domains of Eukaryotic Transcription Factors |
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Peter E. Wright |
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(579-597) |
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| 22 Predictions of the Occurrence and Structure of Metal-binding Domains in Gene Regulatory Proteins |
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Michael H. Schmidt, Jeremy M. Berg |
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(599-613) |
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